Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321538 | 0.86 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1HTTKMT2AAR | |
| SCHEMBL5325348 | 0.81 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HTTKMT2AAR | |
| SCHEMBL5325906 | 0.80 | KMT2A (0.37) | ALDH1A1HTTKMT2AMAPTAAK1 | |
| SCHEMBL5323899 | 0.78 | AAK1 (0.37) | AAK1 | |
| SCHEMBL34472997 | 0.76 | TDP1 (0.43) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL5323321 | 0.75 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1HTTKMT2AKDM4E | |
| SCHEMBL5329375 | 0.75 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1HTTKMT2AKDM4E | |
| SCHEMBL14397187 | 0.72 | PTGES (0.39) | L3MBTL1ALDH1A1HTTKMT2AKDM4E | |
| SCHEMBL5328476 | 0.71 | KMT2A (0.38) | L3MBTL1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL5325901 | 0.71 | KMT2A (0.38) | L3MBTL1ALDH1A1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |