Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328476 | 1.00 | KMT2A (0.38) | KMT2AMEN1L3MBTL1MYCMAX | |
| SCHEMBL5325906 | 0.83 | KMT2A (0.37) | KMT2AMEN1MYCMAXCTSV | |
| SCHEMBL5325348 | 0.81 | L3MBTL1 (0.43) | KMT2AL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL2477081 | 0.81 | MAPT (0.49) | KMT2AMEN1L3MBTL1CTSVCTSL | |
| SCHEMBL573614 | 0.72 | MAPT (0.53) | KMT2AMEN1L3MBTL1CTSVCTSL | |
| SCHEMBL5321538 | 0.71 | ALDH1A1 (0.39) | KMT2AL3MBTL1ALDH1A1HTTPDCD1 | |
| SCHEMBL5325354 | 0.71 | L3MBTL1 (0.38) | KMT2AL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL573839 | 0.70 | CTSV (0.49) | KMT2AMEN1CTSVCTSLNPC1 | |
| SCHEMBL34472997 | 0.69 | TDP1 (0.43) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL2477351 | 0.68 | CTSV (0.50) | KMT2AMEN1L3MBTL1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |