Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323358 | 0.90 | MAPT (0.46) | TP53MAPTALDH1A1HPGDRXFP1 | |
| SCHEMBL5323078 | 0.89 | TP53 (0.44) | TP53MAPTHSD17B10KDM4EGAA | |
| SCHEMBL5324564 | 0.88 | MAPT (0.61) | TP53MAPTALDH1A1HPGDRXFP1 | |
| SCHEMBL5326013 | 0.86 | KDM4E (0.58) | TP53MAPTALDH1A1HPGDRXFP1 | |
| SCHEMBL5326087 | 0.75 | MEN1 (0.46) | TP53MAPTALDH1A1GAALMNA | |
| SCHEMBL3198822 | 0.71 | TP53 (1.00) | TP53MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL5321302 | 0.66 | MAPT (0.39) | TP53MAPTALDH1A1RXFP1KDM4E | |
| SCHEMBL3196889 | 0.64 | TP53 (0.85) | TP53MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL3193574 | 0.64 | TP53 (0.85) | TP53MAPTALDH1A1RXFP1HSD17B10 | |
| SCHEMBL13417543 | 0.63 | MEN1 (0.71) | TP53MAPTALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |