Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325470 | 0.86 | TP53 (0.55) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL5323358 | 0.80 | MAPT (0.46) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL5324564 | 0.79 | MAPT (0.61) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL3198921 | 0.73 | HSD17B10 (1.00) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL5326087 | 0.72 | MEN1 (0.46) | GAAALDH1A1MAPTTSHRTP53 | |
| SCHEMBL15017217 | 0.65 | ALDH1A1 (0.50) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL5321302 | 0.64 | MAPT (0.39) | KDM4EALDH1A1MAPTRXFP1TP53 | |
| SCHEMBL4016957 | 0.63 | KDM4E (0.44) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL15800694 | 0.62 | PLD1 (0.73) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL21353591 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |