Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325470 | 0.89 | TP53 (0.55) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL5323358 | 0.81 | MAPT (0.46) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL5326013 | 0.80 | KDM4E (0.58) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL3189060 | 0.75 | TP53 (0.79) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL5326087 | 0.69 | MEN1 (0.46) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL4311842 | 0.67 | POLB (0.50) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL27583942 | 0.64 | SIRT6 (0.60) | SIRT6LMNAMAPTMEN1KMT2A | |
| SCHEMBL8760113 | 0.64 | SIRT6 (0.56) | SIRT6LMNAMAPTMEN1KMT2A | |
| SCHEMBL4018419 | 0.64 | MAPT (0.47) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL27591247 | 0.63 | SIRT6 (0.52) | SIRT6LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |