SCHEMBL532562

SCHEMBL532562

O=C(Cc1cc(=O)oc2cc(O)ccc12)NCCCCCCO

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.60
ACHE P22303 5/20 0.60
LCK P06239 2/20 0.60
FYN P06241 1/20 0.60
AKR1B1 P15121 1/20 0.60
GRB2 P62993 1/20 0.60
ALDH1A1 P00352 3/20 0.58
GAA P10253 3/20 0.58
KDM4E B2RXH2 2/20 0.58
GLA P06280 2/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
HSD17B10 Q99714 1/20 0.58
HSD17B3 P37058 6/20 0.53
ERAP1 Q9NZ08 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL724773 0.91 LCK (0.63) BCHEACHELCKFYNAKR1B1
SCHEMBL723311 0.91 LCK (0.63) BCHEACHELCKFYNAKR1B1
SCHEMBL8097195 0.90 LCK (0.65) BCHEACHELCKFYNAKR1B1
SCHEMBL725498 0.89 BCHE (0.58) BCHEACHELCKFYNAKR1B1
SCHEMBL10035655 0.88 LCK (0.60) BCHEACHELCKFYNAKR1B1
SCHEMBL2760317 0.87 LCK (0.61) BCHEACHELCKFYNAKR1B1
SCHEMBL10035521 0.84 LCK (0.64) BCHEACHELCKFYNAKR1B1
SCHEMBL726886 0.84 ALDH1A1 (0.56) BCHEACHELCKFYNAKR1B1
SCHEMBL24062584 0.83 ALDH1A1 (0.60) BCHEACHELCKFYNAKR1B1
SCHEMBL716590 0.83 ALDH1A1 (0.57) BCHEACHELCKFYNAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1430147-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2013-05-22 EP disclosed
EP-1235938-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2012-02-08 EP disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 US disclosed
US-7662942-B2 Oligonucleotide probes containing two labels useful in hybridization assays Elitech Holdings, B.V. (NL) 2010-02-16 US disclosed
EP-1430147-A4 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2008-06-25 EP disclosed
US-20060292589-A1 Oligonucleotide probes containing two labels useful in hybridization assays EPOCH BIOSCIENCES, INC. (US) 2006-12-28 US disclosed
US-20040191796-A1 Fluorescent quenching detection reagents and methods EPOCH PHARMACEUTICALS, INC. (US) 2004-09-30 US disclosed
US-6790945-B2 OLIGONUCLEOTIDE PROBES CONTAINING TWO LABELS USEFUL IN HYBRIDIZATION ASSAYS EPOCH BIOSCIENCES, INC. 2004-09-14 US disclosed
EP-1430147-A1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS Epoch Biosciences, Inc. (US) 2004-06-23 EP disclosed
US-6727356-B1 AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION EPOCH PHARMACEUTICALS, INC. 2004-04-27 US disclosed
US-6699975-B2 OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION EPOCH BIOSCIENCES, INC. 2004-03-02 US disclosed
US-6653473-B2 Nucleotide sequences for use as diagnostic tool in genetic analysis EPOCH BIOSCIENCES, INC. 2003-11-25 US disclosed
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression EPOCH BIOSCIENCES, INC. (US) 2003-05-22 US disclosed
US-20030008304-A1 Fluorescent quenching detection reagents and methods EPOCH BIOSCIENCES, INC. (US) 2003-01-09 US disclosed
WO-2002099141-A1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES, INC. (US) 2002-12-12 WO disclosed
US-20020155484-A1 Fluorescent quenching detection reagents and methods EPOCH PHARMACEUTICALS, INC. (US) 2002-10-24 US disclosed
EP-1235938-A2 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS Epoch Biosciences, Inc. (US) 2002-09-04 EP disclosed
US-20020034754-A1 Fluorescent quenching detection reagents and methods ELITECHGROUP, INC. 2002-03-21 US disclosed
WO-2001042505-A2 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES, INC. (US) 2001-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008304-A1 Fluorescent quenching detection reagents and methods DDX5, DDX21, DCLRE1B BCHE 4146/4885ACHE 4087/4885LCK 3347/4885
US-20020034754-A1 Fluorescent quenching detection reagents and methods DDX5, DDX21, DCLRE1B BCHE 4146/4885ACHE 4087/4885LCK 3347/4885
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS DDX5, DDX21, DCLRE1B BCHE 3905/4885ACHE 3956/4885LCK 3110/4885
US-20060292589-A1 Oligonucleotide probes containing two labels useful in hybridization assays DCLRE1B, DDX21, DCLRE1A BCHE 4635/4885ACHE 4840/4885LCK 3374/4885
US-20020155484-A1 Fluorescent quenching detection reagents and methods IPO4, PTBP3, DDX5 BCHE 4757/4885ACHE 3225/4885LCK 2022/4885
US-20040191796-A1 Fluorescent quenching detection reagents and methods DDX5, IPO4, DBF4 BCHE 4622/4885ACHE 3143/4885LCK 2253/4885
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression DCLRE1B, SNRPE, ZFR BCHE 4161/4885ACHE 4771/4885LCK 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.