Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | UBA1 | P22314 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384437 | 1.00 | MAPT (0.33) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL5388942 | 0.88 | KDM4E (0.36) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL533193 | 0.85 | MAPT (0.44) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL532457 | 0.74 | BRD4 (0.37) | MAPTGAAALDH1A1HPGD | |
| SCHEMBL3641489 | 0.70 | PARP1 (0.30) | — | |
| SCHEMBL533321 | 0.70 | KDM4E (0.45) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL3419819 | 0.69 | FABP5 (0.39) | MAPTGAAKMT2ATSHR | |
| SCHEMBL7132853 | 0.63 | MAPT (0.53) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL3419671 | 0.61 | GAA (0.41) | MAPTGAAKDM4EALDH1A1HPGD | |
| SCHEMBL9408601 | 0.58 | MAPT (0.46) | MAPTGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046972-A2 | COMPOSITIONS AND METHODS FOR SUPPRESSING PRIMER INTERACTIONS | Life Technologies Corporation (US) | 2011-04-21 | — | — | WO | claimed |
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1235938-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2011046972-A2 | COMPOSITIONS AND METHODS FOR SUPPRESSING PRIMER INTERACTIONS | Life Technologies Corporation (US) | 2011-04-21 | — | — | WO | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| EP-1430147-A4 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2008-06-25 | — | — | EP | disclosed |
| US-20060292589-A1 | Oligonucleotide probes containing two labels useful in hybridization assays | EPOCH BIOSCIENCES, INC. (US) | 2006-12-28 | — | — | US | disclosed |
| US-20040191796-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-6790945-B2 | OLIGONUCLEOTIDE PROBES CONTAINING TWO LABELS USEFUL IN HYBRIDIZATION ASSAYS | EPOCH BIOSCIENCES, INC. | 2004-09-14 | — | — | US | disclosed |
| EP-1430147-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | Epoch Biosciences, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2002099141-A9 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2004-05-27 | — | — | WO | disclosed |
| US-6727356-B1 | AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION | EPOCH PHARMACEUTICALS, INC. | 2004-04-27 | — | — | US | disclosed |
| US-6699975-B2 | OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION | EPOCH BIOSCIENCES, INC. | 2004-03-02 | — | — | US | disclosed |
| US-6653473-B2 | Nucleotide sequences for use as diagnostic tool in genetic analysis | EPOCH BIOSCIENCES, INC. | 2003-11-25 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002099141-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | US | disclosed |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | ELITECHGROUP, INC. | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | MAPT 4772/4885GAA 1168/4885KDM4E 4634/4885 |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | MAPT 4772/4885GAA 1168/4885KDM4E 4634/4885 |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | MAPT 4706/4885GAA 1153/4885KDM4E 4651/4885 |
| US-20060292589-A1 | Oligonucleotide probes containing two labels useful in hybridization assays | DCLRE1B, DDX21, DCLRE1A | MAPT 4727/4885GAA 1978/4885KDM4E 4819/4885 |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | IPO4, PTBP3, DDX5 | MAPT 4738/4885GAA 3253/4885KDM4E 3864/4885 |
| US-20040191796-A1 | Fluorescent quenching detection reagents and methods | DDX5, IPO4, DBF4 | MAPT 4825/4885GAA 3182/4885KDM4E 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.