Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3495656 | 0.78 | HTR6 (0.33) | BRD4CREBBPHTR6BUB1PIK3CD | |
| SCHEMBL3419819 | 0.78 | FABP5 (0.39) | TP53GAAMAPT | |
| SCHEMBL532382 | 0.76 | MAPT (0.36) | ALDH1A1TP53HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL532722 | 0.74 | MAPT (0.33) | ALDH1A1HPGDGAAMAPT | |
| SCHEMBL5384437 | 0.74 | MAPT (0.33) | ALDH1A1HPGDGAAMAPT | |
| SCHEMBL532247 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TP53SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL3641489 | 0.73 | PARP1 (0.30) | — | |
| SCHEMBL17498059 | 0.69 | BUB1 (0.47) | BRD4CREBBPHTR6BUB1ALDH1A1 | |
| SCHEMBL12422261 | 0.67 | NOTUM (0.47) | BRD4CREBBPHTR6BUB1CYP1A2 | |
| SCHEMBL3166303 | 0.67 | L3MBTL1 (0.43) | BRD4CREBBPHTR6BUB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | disclosed |
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1235938-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2008-11-27 | — | — | US | disclosed |
| EP-1430147-A4 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2008-06-25 | — | — | EP | disclosed |
| US-7381818-B2 | Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof | EPOCH BIOSCIENCES, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| WO-2002099141-A9 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20040081959-A9 | Using oligonucleotide detectors; hybridization analyzing | EPOCH BIOSCIENCES, INC. (US) | 2004-04-29 | — | — | US | disclosed |
| US-6727356-B1 | AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION | EPOCH PHARMACEUTICALS, INC. | 2004-04-27 | — | — | US | disclosed |
| US-6699975-B2 | OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION | EPOCH BIOSCIENCES, INC. | 2004-03-02 | — | — | US | disclosed |
| US-6653473-B2 | Nucleotide sequences for use as diagnostic tool in genetic analysis | EPOCH BIOSCIENCES, INC. | 2003-11-25 | — | — | US | disclosed |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | EPOCH BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002099141-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | US | disclosed |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | ELITECHGROUP, INC. | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | BRD4 1893/4885CREBBP 598/4885HTR6 1011/4885 |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | BRD4 1893/4885CREBBP 598/4885HTR6 1011/4885 |
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | SSBP1, DDB1, DNA2 | BRD4 910/4885CREBBP 659/4885HTR6 1627/4885 |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | BRD4 2011/4885CREBBP 669/4885HTR6 1182/4885 |
| US-20040081959-A9 | Using oligonucleotide detectors; hybridization analyzing | DCLRE1B, DDX21, DDX41 | BRD4 3676/4885CREBBP 2065/4885HTR6 2787/4885 |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | IPO4, PTBP3, DDX5 | BRD4 337/4885CREBBP 2466/4885HTR6 985/4885 |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | DCLRE1B, SNRPE, ZFR | BRD4 2660/4885CREBBP 1597/4885HTR6 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.