Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.63 |
| ▸ | MAOB | P27338 | 8/20 | 0.63 |
| ▸ | CES1 | P23141 | 6/20 | 0.55 |
| ▸ | TGM2 | P21980 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201784 | 0.86 | MAOB (0.69) | MAOAMAOBCES1TGM2ALDH1A1 | |
| SCHEMBL2246979 | 0.85 | TGM2 (0.73) | MAOAMAOBCES1TGM2SMN1; SMN2 | |
| SCHEMBL12124081 | 0.82 | SMN1; SMN2 (0.47) | MAOAMAOBCES1TGM2SMN1; SMN2 | |
| SCHEMBL11702086 | 0.82 | ALDH1A1 (0.47) | MAOAMAOBCES1TGM2SMN1; SMN2 | |
| SCHEMBL23806091 | 0.81 | SMN1; SMN2 (0.59) | MAOAMAOBTGM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13375281 | 0.81 | MAOA (0.63) | MAOAMAOBCES1TGM2BCHE | |
| SCHEMBL22794312 | 0.81 | ALDH1A1 (0.59) | MAOAMAOBTGM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL19642904 | 0.81 | MAOB (0.63) | MAOAMAOBCES1TGM2BCHE | |
| SCHEMBL13594800 | 0.81 | MAOA (0.58) | MAOAMAOBCES1TGM2ALDH1A1 | |
| SCHEMBL12470147 | 0.81 | MAOA (0.58) | MAOAMAOBCES1TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732460-A | Method for synthesizing indole compound | 常州工程职业技术学院 | 2016-07-06 | — | — | CN | claimed |
| CN-102690226-A | Multi-nitrogen substituted isatin derivative and synthetic method of multi-nitrogen substituted isatin derivative | UNIV GUANGDONG TECHNOLOGY | 2012-09-26 | — | — | CN | claimed |
| CN-105732476-B | A kind of carbazole isatin type compound and its preparation method and purposes | 吉首大学 | 2017-12-01 | — | — | CN | disclosed |
| CN-105732476-A | Carbazole-isatin type compound and preparation method and application thereof | 吉首大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-105732460-A | Method for synthesizing indole compound | 常州工程职业技术学院 | 2016-07-06 | — | — | CN | disclosed |
| CN-102924448-B | Alkaloid cryptolepine analogue quindoline acid compound and preparation method | UNIV BOHAI | 2015-02-25 | — | — | CN | disclosed |
| CN-102924448-A | Alkaloid cryptolepine analogue quindoline acid compound and preparation method | UNIV BOHAI | 2013-02-13 | — | — | CN | disclosed |
| CN-102690226-A | Multi-nitrogen substituted isatin derivative and synthetic method of multi-nitrogen substituted isatin derivative | UNIV GUANGDONG TECHNOLOGY | 2012-09-26 | — | — | CN | disclosed |
| WO-2011054874-A1 | METHOD FOR THE PREPARATION OF 2-AMINO-6-ETHYLBENZOIC ACID | ACTIVE BIOTECH AB (SE) | 2011-05-12 | — | — | WO | disclosed |
| EP-2316818-A1 | Method for the preparation of 2-amino-6-ethylbenzoic acid | Active Biotech AB (SE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2007132280-A1 | ISATIN AND ITS DERIVATIVES FOR USE AS A MEDICAMENT | Szegedi Tudományegyetem (HU) | 2007-11-22 | — | — | WO | disclosed |
| WO-1995020581-A1 | NOVEL HUMAN LEUKOCYTE ELASTASE (HLE) INHIBITORS, AND RELATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SRI INTERNATIONAL (US) | 1995-08-03 | — | — | WO | disclosed |
| US-5428021-A | Administering to inhibit serine proteases | SRI INTERNATIONAL (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4665070-A | SERINE PROTEINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1987-05-12 | — | — | US | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0206323-A1 | 2-Oxy-4H-3,1-benzoxazin-4-one derivatives and related compounds | SYNTEX (U.S.A.) INC. (US) | 1986-12-30 | — | — | EP | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |