SCHEMBL5328046

SCHEMBL5328046

NC(CCC1=CCCN1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.39
GRIA1 P42261 2/20 0.39
GRIA2 P42262 2/20 0.39
GRIA3 P42263 2/20 0.39
GRIA4 P48058 2/20 0.39
GRIK2 Q13002 2/20 0.39
GRIK3 Q13003 2/20 0.39
GRM2 Q14416 3/20 0.39
GRM6 O15303 3/20 0.38
CYP1A2 P05177 2/20 0.38
ALOX15 P16050 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
GSR P00390 2/20 0.37
GRM8 O00222 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRM5 P41594 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326866 0.83 SLC7A5 (0.43) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL25661170 0.73 GRM2 (0.42) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5324248 0.70 GRM2 (0.41) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5285402 0.65 ARG1 (0.44) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL602426 0.63 GSR (0.68) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL8068164 0.63 GSR (0.68) GRIK1GRIA1GRIA2GRIA3GRIA4
Homophenylalanine SCHEMBL44311 0.63 ALPI (0.64) GRIK1GRIA1GRIA2GRIA3GRIA4
Homophenylalanine SCHEMBL1078733 0.63 ALPI (0.64) GRIK1GRIA1GRIA2GRIA3GRIA4
Homophenylalanine SCHEMBL44312 0.63 ALPI (0.64) GRIK1GRIA1GRIA2GRIA3GRIA4
Homophenylalanine SCHEMBL130567 0.63 ALPI (0.64) GRIK1GRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20070258899-A1 Diagnostic and therapeutic agents KARYON-CTT LTD (FI) 2007-11-08 US disclosed
WO-2007113385-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP GRIK1 2914/4885GRIA1 2608/4885GRIA2 3164/4885
US-20070258899-A1 Diagnostic and therapeutic agents YBX1, MLX, TPX2 GRIK1 4162/4885GRIA1 3993/4885GRIA2 4396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.