Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250119 | 0.87 | ADAM17 (0.59) | ADAM17MMP2MMP9MAOBRAB9A | |
| SCHEMBL8250122 | 0.87 | ADAM17 (0.74) | ADAM17MMP2MMP9MAOBRAB9A | |
| SCHEMBL5295735 | 0.84 | ADAM17 (0.78) | ADAM17MMP2MMP9MAOBCA12 | |
| SCHEMBL5281333 | 0.78 | MMP2 (0.52) | ADAM17MMP2MMP9MAOBCA12 | |
| SCHEMBL3267547 | 0.75 | MAOA (0.54) | ADAM17MMP2MMP9MAOBCA12 | |
| SCHEMBL5304680 | 0.74 | ADAM17 (0.78) | ADAM17MMP2MMP9MAOBCA12 | |
| SCHEMBL2403666 | 0.72 | RAB9A (0.59) | ADAM17MMP2MMP9MAOBCA12 | |
| SCHEMBL25934291 | 0.72 | MAOB (0.56) | ADAM17MMP2MMP9MAOBCA12 | |
| SCHEMBL8858225 | 0.72 | MMP2 (0.51) | ADAM17MMP2MMP9MAOBCA12 | |
| Acetic Acid SCHEMBL11097867 | 0.71 | MAOB (0.61) | ADAM17MMP2MMP9MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008037-A1 | NOVEL CHROMEN-2-ONE BASED HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY, THE PREPARATION THEREOF AND A COMPOSITION CONTAINING THE SAME FOR TREATING INFLAMMATORY DISEASE | JEIL PHARMACEUTICAL CO., LTD. (KR) | 2007-01-18 | — | — | WO | disclosed |