SCHEMBL5328145

SCHEMBL5328145

CC(Nc1c(-c2ccc3c(c2Cl)COC3=O)c(Cl)nc2ncnn12)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.32
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5328138 1.00 AAK1 (0.32) AAK1LMNAALDH1A1HPGDTSHR
SCHEMBL5328032 0.92 L3MBTL1 (0.32) LMNAALDH1A1HPGDTSHRSMN1; SMN2
SCHEMBL5328026 0.92 L3MBTL1 (0.32) LMNAALDH1A1HPGDTSHRSMN1; SMN2
SCHEMBL5495636 0.91 LMNA (0.32) LMNAALDH1A1HPGDTSHRSMN1; SMN2
SCHEMBL5495634 0.91 LMNA (0.32) LMNAALDH1A1HPGDTSHRSMN1; SMN2
SCHEMBL5329915 0.91 LMNA (0.35) LMNAALDH1A1HPGDTSHRSMN1; SMN2
SCHEMBL5331106 0.87 CRHR1 (0.32) AAK1LMNAALDH1A1HPGDTSHR
SCHEMBL5329170 0.83
SCHEMBL5329174 0.83
SCHEMBL5329828 0.81 MBOAT4 (0.33) LMNAALDH1A1HPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007147829-A1 AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI BASF SE (DE) 2007-12-27 WO disclosed