Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495634 | 0.92 | LMNA (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5495636 | 0.92 | LMNA (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5328145 | 0.91 | AAK1 (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5328138 | 0.91 | AAK1 (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5331106 | 0.91 | CRHR1 (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5328032 | 0.82 | L3MBTL1 (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5328026 | 0.82 | L3MBTL1 (0.32) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5329828 | 0.82 | MBOAT4 (0.33) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5325221 | 0.77 | LMNA (0.39) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14270926 | 0.75 | EGLN2 (0.38) | LMNATSHRALDH1A1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147829-A1 | AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI | BASF SE (DE) | 2007-12-27 | — | — | WO | disclosed |