Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331053 | 0.87 | QPCT (0.46) | TP53LMNARXFP1MAPTALDH1A1 | |
| SCHEMBL5329065 | 0.87 | LMNA (0.60) | TP53LMNAMAPTALDH1A1TSHR | |
| SCHEMBL7014023 | 0.81 | ALDH1A1 (0.59) | TP53RXFP1MAPTALDH1A1TSHR | |
| SCHEMBL7014019 | 0.81 | TSHR (0.59) | TP53LMNARXFP1MAPTALDH1A1 | |
| SCHEMBL13491499 | 0.80 | NPC1 (0.54) | TP53RXFP1EGLN1KMT2AROCK2 | |
| SCHEMBL4916970 | 0.80 | HPGDS (0.65) | TP53ALDH1A1TSHRNPSR1KMT2A | |
| SCHEMBL4927411 | 0.79 | MEN1 (0.77) | TP53RXFP1MAPTALDH1A1TSHR | |
| SCHEMBL5212964 | 0.79 | ALDH1A1 (0.65) | TP53LMNARXFP1MAPTALDH1A1 | |
| SCHEMBL13491644 | 0.78 | ROCK2 (0.56) | EGLN1ROCK2TAS1R3TAS1R1 | |
| SCHEMBL8759043 | 0.78 | HPGD (0.70) | TP53MAPTALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |