Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083706 | 0.87 | ESR1 (0.67) | ESR1CYP1A2CYP2C9CYP2C19PLAA | |
| SCHEMBL22234295 | 0.86 | ESR1 (0.57) | ESR1CYP1A2CYP2C9CYP2C19PLAA | |
| SCHEMBL25402021 | 0.84 | ESR1 (0.61) | ESR1CYP1A2CYP2C19PLAAALPG | |
| SCHEMBL18839799 | 0.82 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL18839661 | 0.80 | L3MBTL1 (0.45) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL5327638 | 0.79 | ESR1 (0.71) | ESR1PLAAALPGALDH1A1CA12 | |
| SCHEMBL9880609 | 0.78 | ESR1 (0.47) | ESR1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL20068591 | 0.77 | FPR2 (0.47) | ALDH1A1MAPK1L3MBTL1TSHRRAB9A | |
| SCHEMBL25402908 | 0.77 | ESR1 (0.50) | ESR1PLAAALPGALDH1A1L3MBTL1 | |
| SCHEMBL12984606 | 0.77 | ESR1 (0.63) | ESR1PLAAALPGALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | ESR1 4728/4885CYP1A2 4174/4885CYP2C9 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.