Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.30 |
| ▸ | ATP4B | P51164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369428 | 0.83 | GABRA1 (0.37) | KCNMA1TP53TSHR | |
| SCHEMBL1148441 | 0.81 | MGAM (0.36) | KCNMA1MGAMGAASIMGAM2 | |
| SCHEMBL3974239 | 0.77 | KCNMA1 (0.36) | KCNMA1TP53 | |
| SCHEMBL3973590 | 0.76 | KCNMA1 (0.38) | KCNMA1GAAALDH1A1 | |
| SCHEMBL4089989 | 0.75 | MGAM (0.35) | KCNMA1MGAMGAASIMGAM2 | |
| SCHEMBL3972617 | 0.74 | NPC1 (0.38) | GAAALDH1A1TP53 | |
| SCHEMBL3974759 | 0.74 | MAPK9 (0.41) | KCNMA1 | |
| SCHEMBL4088457 | 0.73 | KCNMA1 (0.36) | KCNMA1TSHR | |
| SCHEMBL3973703 | 0.73 | KCNN4 (0.37) | KCNMA1GAAALDH1A1TP53 | |
| SCHEMBL1149533 | 0.72 | HSP90AA1 (0.37) | MGAMGAASIMGAM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139952-A2 | METHOD FOR THE PREPARATION OF TRIAZOLE COMPOUNDS WITH HSP90 MODULATING ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-12-06 | — | — | WO | disclosed |