Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533017 | 0.87 | FFAR4 (0.55) | FFAR4CYTH2MEN1KMT2AALDH1A1 | |
| SCHEMBL532832 | 0.86 | FFAR4 (0.60) | FFAR4ALDH1A1SMN1; SMN2MAPTKEAP1 | |
| SCHEMBL533055 | 0.85 | ALDH1A1 (0.45) | FFAR4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL532880 | 0.85 | FFAR4 (0.56) | FFAR4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL533666 | 0.85 | FFAR4 (0.56) | FFAR4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL533437 | 0.85 | CYTH2 (0.49) | FFAR4CYTH2MEN1KMT2AALDH1A1 | |
| SCHEMBL532776 | 0.85 | FFAR4 (0.54) | FFAR4CYTH2MEN1KMT2AALDH1A1 | |
| SCHEMBL532935 | 0.84 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL534816 | 0.83 | MAPT (0.41) | FFAR4CYTH2MEN1KMT2AALDH1A1 | |
| SCHEMBL533091 | 0.83 | BRPF1 (0.52) | MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |