Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532953 | 0.86 | FFAR4 (0.59) | FFAR4ALDH1A1SMN1; SMN2MAPTKEAP1 | |
| SCHEMBL534062 | 0.83 | ERAP1 (0.52) | ALDH1A1SMN1; SMN2LMNATSHRTP53 | |
| SCHEMBL533017 | 0.83 | FFAR4 (0.55) | FFAR4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL532935 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL532951 | 0.81 | EDNRB (0.45) | FFAR4ALDH1A1BRPF1SMN1; SMN2LMNA | |
| SCHEMBL14288678 | 0.81 | ALDH1A1 (0.52) | ALDH1A1BRPF1HTTSMN1; SMN2LMNA | |
| SCHEMBL534065 | 0.81 | PKM (0.53) | SMN1; SMN2EDNRAALOX15 | |
| SCHEMBL533055 | 0.81 | ALDH1A1 (0.45) | FFAR4ALDH1A1SMN1; SMN2CYP2C9MAPT | |
| SCHEMBL533666 | 0.81 | FFAR4 (0.56) | FFAR4ALDH1A1HTTLMNAMAPT | |
| SCHEMBL532880 | 0.81 | FFAR4 (0.56) | FFAR4ALDH1A1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |