Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533666 | 0.90 | FFAR4 (0.56) | FFAR4MAPTALDH1A1RECQLTP53 | |
| SCHEMBL533055 | 0.90 | ALDH1A1 (0.45) | FFAR4MAPTALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL532880 | 0.90 | FFAR4 (0.56) | FFAR4MAPTALDH1A1RECQLHSD17B10 | |
| SCHEMBL533437 | 0.90 | CYTH2 (0.49) | FFAR4MAPTALDH1A1RECQLCYTH2 | |
| SCHEMBL532776 | 0.89 | FFAR4 (0.54) | FFAR4MAPTALDH1A1RECQLCYTH2 | |
| SCHEMBL534044 | 0.88 | MAPT (0.43) | FFAR4MAPTALDH1A1RECQLCYTH2 | |
| SCHEMBL534816 | 0.87 | MAPT (0.41) | FFAR4MAPTALDH1A1RECQLCYTH2 | |
| SCHEMBL534077 | 0.87 | TSHR (0.47) | FFAR4MAPTALDH1A1RECQLCYTH2 | |
| SCHEMBL532953 | 0.87 | FFAR4 (0.59) | FFAR4MAPTALDH1A1CYTH2SMN1; SMN2 | |
| SCHEMBL533020 | 0.87 | KMT2A (0.51) | FFAR4MAPTALDH1A1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |