Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505720 | 0.86 | MAPT (0.38) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL12834526 | 0.80 | HSD11B1 (0.43) | MAPTNPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL12834528 | 0.80 | ESR1 (0.50) | — | |
| SCHEMBL8639066 | 0.80 | ESR1 (0.50) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL5052389 | 0.79 | ESR1 (0.43) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL12200936 | 0.79 | MAPT (0.49) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4530562 | 0.77 | RAB9A (0.35) | MAPTHTTRAB9ASMN1; SMN2KIF11 | |
| SCHEMBL13577644 | 0.75 | ESR2 (0.44) | MAPT | |
| SCHEMBL9006703 | 0.75 | ALDH1A1 (0.34) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9006533 | 0.75 | PTPN1 (0.38) | MAPTNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005335-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005356-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |