SCHEMBL5329980

SCHEMBL5329980

Cc1ccc(C(F)=C(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
TDP1 Q9NUW8 3/20 0.44
ACHE P22303 3/20 0.44
PKM P14618 2/20 0.42
HTT P42858 2/20 0.42
ATM Q13315 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
HPGD P15428 1/20 0.42
NLRP1 Q9C000 1/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 1/20 0.42
NTSR1 P30989 1/20 0.42
KMT2A Q03164 1/20 0.42
SRD5A2 P31213 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20118491 0.88 ALDH1A1 (0.52) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL726750 0.85 CES2 (0.32) CES2CES1
SCHEMBL22745485 0.81 ALDH1A1 (0.46) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL20118501 0.81 ALDH1A1 (0.46) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL20118718 0.79 ACHE (0.65) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL17288381 0.77 ALDH1A1 (0.52) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL8591250 0.77 BCL2L1 (0.39) LMNASMN1; SMN2MEN1KMT2AGSK3B
SCHEMBL18213881 0.76 ALDH1A1 (0.46) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL7590152 0.74 CES2 (0.50) CES2CES1MEN1KMT2ACA2
SCHEMBL11432823 0.74 MAPT (0.47) ALDH1A1CES2LMNASMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1421126-B1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS (CA) 2007-03-14 EP claimed
US-20060079594-A1 Process for preparing graft copolymer membranes STONE CHARLES 2006-04-13 US claimed
EP-1421125-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2004-05-26 EP claimed
EP-1421126-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2004-05-26 EP claimed
WO-2004026929-A1 PROCESS FOR PREPARING GRAFT COPOLYMERS USEFUL IN MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2004-04-01 WO claimed
US-20040059015-A1 Process for preparing graft copolymers and membranes formed therefrom BALLARD POWER SYSTEMS INC. (CA) 2004-03-25 US claimed
US-20040016693-A1 Process for preparing graft copolymer membranes BALLARD POWER SYSTEMS INC. (CA) 2004-01-29 US claimed
US-20040009305-A1 Process for preparing graft copolymer membranes BALLARD POWER SYSTEMS INC. (CA) 2004-01-15 US claimed
WO-2003018654-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2003-03-06 WO claimed
WO-2003018655-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2003-03-06 WO claimed
JP-1266118-A None JP disclosed
US-20230071261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-03-09 US disclosed
EP-2543656-B1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN DAIKIN IND LTD (JP) 2019-09-25 EP disclosed
EP-3524646-A1 IONIC COMPOUND, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DIODE LG Chem, Ltd. (KR) 2019-08-14 EP disclosed
CN-106631716-B A kind of method and application synthesizing Trifluorovinyl Aryl Ethers class compound 中国科学院上海有机化学研究所 2018-12-18 CN disclosed
US-5175302-A Nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1992-12-29 US disclosed
US-4999429-A Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives ETHYL CORPORATION (US) 1991-03-12 US disclosed
JP-H01266118-A FLUORINATED ACRYLIC COPOLYMER DAIKIN IND LTD 1989-10-24 JP disclosed
US-4837327-A Process for nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1989-06-06 US disclosed
EP-0240726-A2 Resist material DAIKIN INDUSTRIES, LIMITED (JP) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230071261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 ALDH1A1 43/4885CES2 213/4885CES1 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.