Sugi Predict

Sugi Predict / Compounds / SCHEMBL7590152

SCHEMBL7590152

SCHEMBL7590152

FC(F)=C(F)c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 1/20 0.50
▸ CES1 P23141 1/20 0.50
▸ CA1 P00915 3/20 0.46
▸ CA2 P00918 3/20 0.46
▸ BCL2L1 Q07817 1/20 0.42
▸ BAD Q92934 1/20 0.42
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ LTA4H P09960 1/20 0.39
▸ ORAI1 Q96D31 1/20 0.38
▸ ORAI2 Q96SN7 1/20 0.38
▸ ORAI3 Q9BRQ5 1/20 0.38
▸ TRPV6 Q9H1D0 1/20 0.38
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ TNFRSF1A P19438 1/20 0.37
▸ MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL726750 0.87 CES2 (0.32) CES2CES1
SCHEMBL14213079 0.80 BCL2L1 (0.58) CES2CES1CA1CA2BCL2L1
SCHEMBL8591250 0.79 BCL2L1 (0.39) BCL2L1BADNPC1RAB9APTPN1
SCHEMBL11432823 0.77 MAPT (0.47) CES2CA1CA2NPC1RAB9A
SCHEMBL20118718 0.76 ACHE (0.65) CES2CES1CA1CA2MEN1
SCHEMBL17289141 0.75 CES2 (0.55) CES2CES1CA1CA2BCL2L1
SCHEMBL5329980 0.74 ALDH1A1 (0.48) CES2CES1CA2MEN1KMT2A
SCHEMBL14322093 0.74 CES2 (0.48) CES2CES1CA1CA2
SCHEMBL7767055 0.74 CES2 (0.48) CES2CES1CA1CA2RAB9A
SCHEMBL285854 0.73 CES1 (0.43) CES2CES1CA1CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6437011-B2 POROUS SUBSTRATE IMPREGNATED WITH ALPHA,BETA,BETA-TRIFLUOROSTYRENE HOMO- AND COPOLYMERS, SULFONATED OR CONTAINING P-SULFONYLFLUORIDE-ALPHA,BETA,BETA-TRIFLUOROSTYRENE COMONOMER; MEMBRANE ELECTROLYTES BALLARD POWER SYSTEMS INC. (CA) 2002-08-20 — — US claimed
WO-2024125835-A1 BLOCK COPOLYMER, METHOD FOR PRODUCING A BLOCK COPOLYMER, MEMBRANE, USE OF A MEMBRANE, AND METHOD FOR PRODUCING A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-06-20 — — WO disclosed
CN-112811974-B Novel aryl trifluoroethylene synthesized by arylation reagent and preparation method thereof 中昊晨光化工研究院有限公司 2022-03-22 — — CN disclosed
CN-112624898-B Synthetic method of aryl trifluoroethylene compound 中昊晨光化工研究院有限公司 2022-03-22 — — CN disclosed
CN-112811974-A Novel aryl trifluoroethylene synthesized by arylation reagent and preparation method thereof 中昊晨光化工研究院有限公司 2021-05-18 — — CN disclosed
CN-112624898-A Synthetic method of aryl trifluoroethylene compound 中昊晨光化工研究院有限公司 2021-04-09 — — CN disclosed
EP-2543656-B1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN DAIKIN IND LTD (JP) 2019-09-25 — — EP disclosed
US-9067200-B2 Method for producing substituted fluorine-containing olefin DAIKIN INDUSTRIES, LTD. (JP) 2015-06-30 — — US disclosed
US-8648202-B2 Bis(perfluoroalkyl)phosphinous acids and derivatives and use thereof MERCK PATENT GMBH (DE) 2014-02-11 — — US disclosed
US-8648202-B2 Bis(perfluoroalkyl)phosphinous acids and derivatives and use thereof MERCK PATENT GMBH (DE) 2014-02-11 — — US disclosed
US-20120330072-A1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN OSAKA UNIVERSITY (JP) 2012-12-27 — — US disclosed
WO-2012142956-A1 PREPARATION METHOD OF TRIFLUOROSTYRENE COMPOUND 中国科学院上海有机化学研究所 (CN) 2012-10-26 — — WO disclosed
US-20110124873-A1 Bis(perfluoralkyl)phosphinous acids and derivatives and use thereof MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-26 — — US disclosed
US-20110124873-A1 Bis(perfluoralkyl)phosphinous acids and derivatives and use thereof MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-26 — — US disclosed
EP-0720628-B1 TRIFLUOROSTYRENE AND SUBSTITUTED TRIFLUOROSTYRENE COPOLYMERIC COMPOSITIONS AND ION-EXCHANGE MEMBRANES FORMED THEREFROM BALLARD POWER SYSTEMS (CA) 2000-08-09 — — EP disclosed
US-5773480-A USED AS SOLID POLYMER ELECTROLYTES IN ELECTROCHEMICAL FUEL CELLS BALLARD POWER SYSTEMS INC. (CA) 1998-06-30 — — US disclosed
EP-0720628-A1 TRIFLUOROSTYRENE AND SUBSTITUTED TRIFLUOROSTYRENE COPOLYMERIC COMPOSITIONS AND ION-EXCHANGE MEMBRANES FORMED THEREFROM BALLARD POWER SYSTEMS INC. (CA) 1996-07-10 — — EP disclosed
US-5498639-A ELECTROCHEMICAL FUEL CELLS BALLARD POWER SYSTEMS INC. (CA) 1996-03-12 — — US disclosed
US-5422411-A Fluoropolymers for electrolytic cells BALLARD POWER SYSTEMS INC. (CA) 1995-06-06 — — US disclosed
WO-1995008581-A1 TRIFLUOROSTYRENE AND SUBSTITUTED TRIFLUOROSTYRENE COPOLYMERIC COMPOSITIONS AND ION-EXCHANGE MEMBRANES FORMED THEREFROM BALLARD POWER SYSTEMS INC. (CA) 1995-03-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120330072-A1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN FOS, POF1B, FOSB CES2 3808/4885CES1 4572/4885CA1 731/4885
US-20110124873-A1 Bis(perfluoralkyl)phosphinous acids and derivatives and use thereof PFKFB3, PFAS, PFKFB2 CES2 1105/4885CES1 1009/4885CA1 711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.