Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324143 | 0.88 | HTR6 (0.42) | HTR6HTR7PPARG | |
| SCHEMBL5333623 | 0.85 | HTR6 (0.44) | HTR6HTR7KLK7 | |
| SCHEMBL5332248 | 0.84 | HTR6 (0.44) | HTR6 | |
| SCHEMBL5424103 | 0.83 | DDR1 (0.35) | HTR6DDR1 | |
| SCHEMBL5330034 | 0.83 | HTR6 (0.41) | HTR6PPARGKLK7DDR1 | |
| SCHEMBL5333545 | 0.83 | HTR6 (0.41) | HTR6 | |
| SCHEMBL5331263 | 0.82 | PTGDR2 (0.44) | HTR6 | |
| SCHEMBL5331698 | 0.81 | HTR6 (0.54) | HTR6 | |
| SCHEMBL5326862 | 0.80 | HTR6 (0.49) | HTR6HTR7PPARG | |
| SCHEMBL5326887 | 0.80 | HTR6 (0.40) | HTR6PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |