Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307210 | 0.91 | NPC1 (0.69) | HCAR2RAB9ANPC1LTB4RSMN1; SMN2 | |
| SCHEMBL5308463 | 0.88 | HCAR2 (0.64) | HCAR2RAB9ANPC1LTB4RSMN1; SMN2 | |
| SCHEMBL5306921 | 0.84 | LTB4R (0.53) | HCAR2RAB9ANPC1LTB4RSMN1; SMN2 | |
| SCHEMBL5066827 | 0.82 | HCAR2 (0.83) | HCAR2RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5299672 | 0.82 | HCAR2 (0.53) | HCAR2LTB4RSMN1; SMN2KDM4E | |
| SCHEMBL5292231 | 0.80 | LMNA (0.57) | SMN1; SMN2MEN1KMT2AMAPK8TDP1 | |
| SCHEMBL5293614 | 0.79 | RAB9A (0.54) | HCAR2RAB9ANPC1LTB4RSMN1; SMN2 | |
| SCHEMBL5061069 | 0.78 | RAB9A (0.86) | HCAR2RAB9ANPC1LTB4RSMN1; SMN2 | |
| SCHEMBL5330760 | 0.76 | HCAR2 (0.72) | HCAR2RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL5330080 | 0.76 | HCAR2 (0.72) | HCAR2RAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | claimed |
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |