Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327555 | 0.88 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL13544514 | 0.79 | PPARG (0.61) | MAPTTP53LMNAALDH1A1TSHR | |
| SCHEMBL5329065 | 0.78 | LMNA (0.60) | MAPTSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL13544741 | 0.77 | PPARG (0.61) | MAPTTP53LMNAALDH1A1TSHR | |
| SCHEMBL13544512 | 0.76 | MAPT (0.61) | MAPTTP53LMNAALDH1A1TSHR | |
| SCHEMBL8759043 | 0.75 | HPGD (0.70) | MAPTSMN1; SMN2TP53ALDH1A1TSHR | |
| SCHEMBL3524782 | 0.75 | TAS1R3 (0.59) | MAPTTP53LMNAALDH1A1TSHR | |
| SCHEMBL5328751 | 0.74 | TP53 (0.56) | MAPTTP53LMNAALDH1A1TSHR | |
| SCHEMBL14758444 | 0.74 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL2261220 | 0.74 | APLNR (0.65) | MAPTALDH1A1TSHRNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |