Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331037 | 1.00 | POLB (0.62) | POLBALDH1A1NPSR1KDM4EHTT | |
| SCHEMBL5332052 | 0.90 | POLB (0.58) | POLBALDH1A1NPSR1KDM4EHTT | |
| SCHEMBL5332046 | 0.90 | POLB (0.58) | POLBALDH1A1NPSR1KDM4EHTT | |
| SCHEMBL5332252 | 0.86 | POLB (0.68) | POLBALDH1A1NPSR1KDM4EHTT | |
| SCHEMBL5339948 | 0.81 | PTK2 (0.67) | POLBALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL5339956 | 0.81 | PTK2 (0.67) | POLBALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL5332328 | 0.81 | PKM (0.66) | POLBALDH1A1NPSR1RECQLKMT2A | |
| SCHEMBL14542391 | 0.79 | ALDH1A1 (0.65) | POLBALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL5339920 | 0.79 | SMN1; SMN2 (0.62) | POLBALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL5339915 | 0.79 | SMN1; SMN2 (0.62) | POLBALDH1A1KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |