Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331037 | 0.86 | POLB (0.62) | POLBALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL5331032 | 0.86 | POLB (0.62) | POLBALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL5332052 | 0.84 | POLB (0.58) | POLBALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL5332046 | 0.84 | POLB (0.58) | POLBALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL5333033 | 0.84 | ALDH1A1 (0.75) | ALDH1A1KMT2AMAPK1TSHRMEN1 | |
| SCHEMBL5332328 | 0.83 | PKM (0.66) | POLBALDH1A1NPSR1RECQLKMT2A | |
| SCHEMBL5328964 | 0.83 | SMN1; SMN2 (0.75) | POLBALDH1A1KDM4EKMT2AMAPK1 | |
| SCHEMBL5331937 | 0.74 | ADORA1 (0.47) | POLBALDH1A1KDM4EKMT2AMAPK1 | |
| SCHEMBL5412718 | 0.73 | MAPT (0.60) | POLBALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL15986445 | 0.72 | ALDH1A1 (0.77) | POLBALDH1A1KDM4ERECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |