Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDXK | O00764 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307871 | 0.87 | GAA (0.59) | GAACA2CA9CA1KMT2A | |
| SCHEMBL4016022 | 0.75 | KDM4E (0.61) | GAACA2CA9CA1KMT2A | |
| SCHEMBL14899351 | 0.71 | LMNA (0.65) | GAACA2CA9CA1KMT2A | |
| SCHEMBL11469014 | 0.71 | KDM4E (0.47) | GAAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12808226 | 0.68 | CA12 (0.75) | GAACA2CA9CA1KMT2A | |
| SCHEMBL9461115 | 0.67 | ALDH1A1 (0.51) | GAAKMT2AHDAC1HDAC3HDAC2 | |
| SCHEMBL370882 | 0.64 | KDM4E (0.54) | GAAKMT2AHDAC1HDAC3HDAC2 | |
| SCHEMBL893345 | 0.64 | HSD17B10 (0.60) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30093231 | 0.64 | CXCR4 (0.53) | GAACA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL7673743 | 0.63 | IDO1 (0.50) | GAACA2CA9KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |