Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579182 | 0.78 | RAB9A (0.55) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| Hydrochloric Acid SCHEMBL5579229 | 0.77 | RAB9A (0.57) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| SCHEMBL5339148 | 0.72 | DHFR (0.39) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| SCHEMBL11432404 | 0.67 | TUBB4A (0.48) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| SCHEMBL5579172 | 0.65 | TUBB3 (0.53) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| SCHEMBL114319 | 0.64 | CA1 (0.61) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| SCHEMBL5579326 | 0.64 | CSF1R (0.50) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| SCHEMBL6181267 | 0.64 | CSF1R (0.80) | EGFRPDGFRBKDRPDGFRACSF1R | |
| SCHEMBL5579174 | 0.64 | RAB9A (0.62) | EGFRPDGFRBKDRTUBB3TUBB4A | |
| Hydrochloric Acid SCHEMBL6180769 | 0.63 | CSF1R (0.81) | EGFRPDGFRBKDRPDGFRACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056214-A2 | N-ALKYL-N-ARYL-THIENOPYRIMIDIN-R-AMINES AND USES THEREOF | CYTOVIA, INC (US) | 2007-05-18 | — | — | WO | disclosed |