Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB3 | Q13509 | 7/20 | 0.53 |
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | KDR | P35968 | 7/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.53 |
| ▸ | TUBB | P07437 | 5/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579272 | 0.82 | TUBB3 (0.53) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL5579178 | 0.79 | TUBB3 (0.60) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL5579136 | 0.76 | TUBB4A (0.64) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL21823045 | 0.74 | MAPK1 (0.63) | MAPK1LPAR1LPAR2 | |
| SCHEMBL4783688 | 0.73 | EGFR (0.49) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL5579174 | 0.70 | RAB9A (0.62) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL5579326 | 0.70 | CSF1R (0.50) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL3123888 | 0.69 | KDR (1.00) | TUBB3EGFRKDRPDGFRBTUBB4A | |
| SCHEMBL13920413 | 0.69 | NPC1 (0.47) | MAPK1LPAR1LPAR2 | |
| SCHEMBL5579341 | 0.68 | EGFR (0.56) | TUBB3EGFRKDRPDGFRBTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-09-13 | — | — | US | claimed |
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP10, CASP4, CASP3 | TUBB3 1358/4885EGFR 1334/4885KDR 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.