Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329662 | 0.81 | EPHX2 (0.41) | EPHX2L3MBTL1 | |
| SCHEMBL5324557 | 0.81 | TSHR (0.46) | TSHRL3MBTL1LMNASMN1; SMN2KMT2A | |
| SCHEMBL5332969 | 0.78 | L3MBTL1 (0.39) | EPHX2L3MBTL1 | |
| SCHEMBL5329666 | 0.77 | EPHX2 (0.40) | EPHX2L3MBTL1 | |
| SCHEMBL5332965 | 0.75 | GPR88 (0.39) | TSHRL3MBTL1LMNACYP1A2CYP2D6 | |
| SCHEMBL5331537 | 0.74 | TSHR (0.46) | TSHRL3MBTL1NPY5R | |
| SCHEMBL5329549 | 0.72 | TDP1 (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL5331113 | 0.72 | TSHR (0.43) | TSHRSMN1; SMN2CTSLCTSBCTSK | |
| SCHEMBL5406520 | 0.72 | L3MBTL1 (0.38) | TSHREPHX2L3MBTL1LMNACYP1A2 | |
| SCHEMBL5469999 | 0.70 | L3MBTL1 (0.40) | TSHREPHX2L3MBTL1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |