Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 6/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331113 | 0.88 | TSHR (0.43) | TSHRLTA4HKLK7FAAHPOLB | |
| SCHEMBL5324604 | 0.84 | TSHR (0.46) | TSHRKLK7FAAHALDH1A1MAPK1 | |
| SCHEMBL5324557 | 0.80 | TSHR (0.46) | TSHRKLK7POLBALDH1A1MAPK1 | |
| SCHEMBL5331540 | 0.80 | ADRB2 (0.42) | TSHRLTA4HPOLBALDH1A1MAPK1 | |
| SCHEMBL5331057 | 0.78 | FAAH (0.38) | FAAHL3MBTL1CASP1 | |
| SCHEMBL5329549 | 0.78 | TDP1 (0.39) | LTA4HFAAH | |
| SCHEMBL5331767 | 0.77 | FAAH (0.40) | FAAHOPRM1OPRD1OPRK1 | |
| SCHEMBL5331609 | 0.74 | TSHR (0.43) | TSHRL3MBTL1NPY5R | |
| SCHEMBL5324746 | 0.74 | FAAH (0.40) | FAAHCASP1 | |
| SCHEMBL5329662 | 0.73 | EPHX2 (0.41) | FAAHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |