Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265952 | 0.79 | TAAR1 (0.45) | HSP90AB1HSD17B10MAPK1ALDH1A1TSHR | |
| SCHEMBL3814453 | 0.78 | ALDH1A1 (0.52) | POLBALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL541447 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EHPGDKMT2A | |
| SCHEMBL5331477 | 0.75 | ALDH1A1 (0.58) | HSD17B10MAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL5332252 | 0.74 | POLB (0.68) | POLBMAPK1ALDH1A1TSHRKDM4E | |
| SCHEMBL5334168 | 0.73 | GPBAR1 (0.50) | POLBHSP90AB1HSD17B10MAPK1ALDH1A1 | |
| SCHEMBL5332328 | 0.72 | PKM (0.66) | POLBHSD17B10MAPK1ALDH1A1TSHR | |
| SCHEMBL1422874 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HPGD | |
| SCHEMBL24128943 | 0.71 | TAAR1 (0.53) | HSD17B10MAPK1ALDH1A1TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL4942544 | 0.70 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |