Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1F | P30939 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314774 | 0.89 | PSEN1 (0.43) | HTR6TERTALDH1A1HTR7 | |
| Hydrochloric Acid SCHEMBL5334181 | 0.83 | HTR6 (0.43) | HTR6HTR2AHTR2CHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL5332344 | 0.78 | HTR2A (0.54) | HTR6HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL5313662 | 0.77 | TERT (0.38) | HTR6TERTHTR2AHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL5330712 | 0.75 | HTR6 (0.43) | HTR6HTR2AHTR2CKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5331946 | 0.75 | HTR6 (0.55) | HTR6HTR2AHTR2CHTR1AHTR1D | |
| SCHEMBL5332993 | 0.74 | MPO (0.45) | HTR6TERTHTR2AHTR2CKDM4E | |
| Hydrochloric Acid SCHEMBL5334206 | 0.72 | KMT2A (0.37) | HTR6HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL5330718 | 0.71 | HTR6 (0.54) | HTR6HTR2AHTR2CALDH1A1MAPT | |
| SCHEMBL5332470 | 0.70 | HTR6 (0.47) | HTR6HTR1AHTR1DHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |