Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5334181 | 0.88 | HTR6 (0.43) | MPOHTR2AHTR2CHTR1ASLC6A4 | |
| SCHEMBL5330477 | 0.87 | HTR2A (0.57) | MPOHTR2AHTR2CHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL5331946 | 0.75 | HTR6 (0.55) | MPOHTR2AHTR2CHTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL5330712 | 0.75 | HTR6 (0.43) | HTR2AHTR2CHTR1ASLC6A4PTGS2 | |
| SCHEMBL5332463 | 0.74 | HTR6 (0.38) | HTR2AHTR2CHTR1ASLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL5332344 | 0.74 | HTR2A (0.54) | HTR2AHTR2CHTR1ASLC6A4DRD2 | |
| SCHEMBL5333021 | 0.72 | MPO (0.45) | MPOHTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL8191018 | 0.69 | HTR6 (0.42) | MPOHTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL5333006 | 0.68 | HTR6 (0.52) | MPOHTR1ADRD2MAPTHTR6 | |
| SCHEMBL5330718 | 0.68 | HTR6 (0.54) | HTR2AHTR2CHTR1APTGS2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |