Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332387 | 0.78 | LMNA (0.39) | CA2ALOX5CYP2D6 | |
| SCHEMBL5503364 | 0.72 | CA2 (0.40) | CA2 | |
| SCHEMBL354403 | 0.71 | CA2 (0.36) | CA2ALOX5 | |
| SCHEMBL917453 | 0.70 | CA2 (0.46) | CA2CYP2D6 | |
| SCHEMBL5332669 | 0.70 | SIGMAR1 (0.35) | CA2CYP2D6 | |
| SCHEMBL6009871 | 0.69 | CA1 (0.44) | CA2CYP2D6 | |
| SCHEMBL353848 | 0.69 | SLC2A1 (0.38) | CA2 | |
| SCHEMBL7919805 | 0.69 | CA2 (0.45) | CA2CYP2D6 | |
| SCHEMBL918439 | 0.69 | KMT2A (0.38) | CA2 | |
| SCHEMBL918428 | 0.69 | KMT2A (0.38) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |