Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542257 | 0.86 | MCHR1 (0.72) | MCHR1KCNH2 | |
| SCHEMBL5307582 | 0.84 | MCHR1 (0.54) | MCHR1KCNH2ACHE | |
| SCHEMBL14542518 | 0.83 | ACHE (0.43) | MCHR1ACHE | |
| SCHEMBL1605047 | 0.73 | HTR2B (0.66) | MCHR1KCNH2 | |
| SCHEMBL5312468 | 0.72 | MCHR1 (0.69) | MCHR1KCNH2 | |
| SCHEMBL5312221 | 0.72 | MCHR1 (0.60) | MCHR1KCNH2 | |
| SCHEMBL4125253 | 0.71 | SIGMAR1 (0.62) | MCHR1 | |
| SCHEMBL4753138 | 0.70 | MEN1 (0.66) | MCHR1KCNH2 | |
| SCHEMBL5308436 | 0.70 | MCHR1 (0.66) | MCHR1KCNH2 | |
| SCHEMBL5364039 | 0.70 | BRD4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042668-A1 | DERIVATIVES OF 1-AMINO-ISOQUINOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS IN THE TREATMENT OF A DYSFUNCTION ASSOCIATED WITH MCH RECEPTOR 1 | SANOFI-AVENTIS (FR) | 2007-04-19 | — | — | WO | disclosed |