Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338305 | 0.93 | MAPT (0.48) | MAPTSMN1; SMN2HTTMEN1NPC1 | |
| SCHEMBL8227750 | 0.88 | MAPT (0.46) | MAPTSMN1; SMN2HTTMEN1NPC1 | |
| SCHEMBL8236528 | 0.83 | CXCR3 (0.41) | MAPTSMN1; SMN2HTTMEN1NPC1 | |
| SCHEMBL5334912 | 0.83 | GSK3B (0.50) | GSK3BMAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL8236027 | 0.83 | KDM4E (0.40) | MAPTSMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL8236015 | 0.82 | MAPT (0.43) | GSK3BMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL5341032 | 0.80 | TDP1 (0.39) | MAPTSMN1; SMN2HTTMEN1NPC1 | |
| SCHEMBL8235194 | 0.80 | MAPT (0.49) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL8233443 | 0.79 | ADORA1 (0.42) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL8236014 | 0.79 | MAPT (0.50) | MAPTSMN1; SMN2HTTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |