Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334907 | 0.83 | GSK3B (0.43) | GSK3BMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5338305 | 0.75 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8227750 | 0.71 | MAPT (0.46) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8236014 | 0.70 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9911482 | 0.68 | GAA (0.46) | MAPTRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5320148 | 0.68 | ALDH1A1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8236528 | 0.67 | CXCR3 (0.41) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL4028435 | 0.67 | GSK3B (1.00) | GSK3B | |
| SCHEMBL24137901 | 0.65 | LMNA (0.51) | MAPTRAB9APKMKDM4EMEN1 | |
| SCHEMBL8236027 | 0.65 | KDM4E (0.40) | MAPTSMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |