Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338305 | 0.85 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL5320148 | 0.83 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8235496 | 0.82 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL5334907 | 0.79 | GSK3B (0.43) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8227750 | 0.78 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL28428243 | 0.78 | ADORA3 (0.56) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL8236528 | 0.76 | CXCR3 (0.41) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8233961 | 0.76 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8038965 | 0.75 | TMIGD3 (0.50) | MAPTSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL8228005 | 0.74 | TSHR (0.44) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |