Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233396 | 0.85 | ADORA1 (0.41) | ADORA1KDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL5338305 | 0.85 | MAPT (0.48) | ADORA1KDM4EADORA3ADORA2ANPC1 | |
| SCHEMBL8236017 | 0.82 | KDM4E (0.41) | ADORA1KDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL8233368 | 0.82 | ALDH1A1 (0.49) | ADORA1KDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL5334907 | 0.79 | GSK3B (0.43) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8227750 | 0.78 | MAPT (0.46) | KDM4ETMIGD3NPC1ALDH1A1RAB9A | |
| SCHEMBL8236528 | 0.78 | CXCR3 (0.41) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8235194 | 0.77 | MAPT (0.49) | KDM4EALDH1A1POLBHPGDNPSR1 | |
| SCHEMBL27564482 | 0.74 | ALDH1A1 (0.50) | ADORA1KDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL8236015 | 0.74 | MAPT (0.43) | ADORA1ADORA3ADORA2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |