Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227750 | 0.95 | MAPT (0.46) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL5338305 | 0.86 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AADORA3 | |
| SCHEMBL5334907 | 0.82 | GSK3B (0.43) | MAPTSMN1; SMN2NPC1RAB9AGSK3B | |
| SCHEMBL8236012 | 0.82 | ALDH1A1 (0.47) | MAPTSMN1; SMN2GABRA2GABRB2ADORA3 | |
| SCHEMBL8236528 | 0.81 | CXCR3 (0.41) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8235194 | 0.77 | MAPT (0.49) | MAPTTP53LMNA | |
| SCHEMBL8233961 | 0.77 | ALDH1A1 (0.56) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL8236027 | 0.76 | KDM4E (0.40) | MAPTSMN1; SMN2LMNA | |
| SCHEMBL8233443 | 0.74 | ADORA1 (0.42) | SMN1; SMN2NPC1RAB9AADORA3ADORA2A | |
| SCHEMBL8237709 | 0.74 | MAPT (0.41) | MAPTSMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |