Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | HTR6 | P50406 | 5/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532878 | 0.93 | FFAR4 (0.60) | FFAR4DRD2DRD3HTR6HTR2A | |
| SCHEMBL533020 | 0.89 | KMT2A (0.51) | FFAR4LMNATP53MAPT | |
| SCHEMBL533123 | 0.85 | FFAR4 (0.42) | FFAR4HTR6LMNATP53POLB | |
| SCHEMBL533017 | 0.83 | FFAR4 (0.55) | FFAR4LMNATP53POLBMAPT | |
| SCHEMBL533055 | 0.81 | ALDH1A1 (0.45) | FFAR4HTR6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL533666 | 0.81 | FFAR4 (0.56) | FFAR4LMNATP53POLBMAPT | |
| SCHEMBL532880 | 0.81 | FFAR4 (0.56) | FFAR4DRD2DRD3HTR6HTR2A | |
| SCHEMBL533437 | 0.81 | CYTH2 (0.49) | FFAR4LMNATP53POLBMAPT | |
| SCHEMBL532776 | 0.81 | FFAR4 (0.54) | FFAR4CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL533091 | 0.79 | BRPF1 (0.52) | CYP1A2CYP3A4CYP2C19LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |