Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332975 | 0.94 | HTR6 (0.50) | HTR6KMT2ADDR1ALDH1A1MEN1 | |
| SCHEMBL5332522 | 0.92 | HSD17B10 (0.42) | HTR6HSD17B10KMT2ADDR1ALDH1A1 | |
| SCHEMBL5328593 | 0.92 | ALDH1A1 (0.46) | HTR6KMT2ADDR1ALDH1A1KDM4E | |
| SCHEMBL5336272 | 0.91 | HSD17B10 (0.45) | HTR6HSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL5331983 | 0.90 | HTR6 (0.52) | HTR6HSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL5333246 | 0.90 | POLB (0.45) | HTR6HSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL5334120 | 0.87 | POLB (0.46) | HTR6KMT2ADDR1ALDH1A1KDM4E | |
| SCHEMBL5333018 | 0.86 | DDR1 (0.43) | HTR6HSD17B10KMT2ADDR1ALDH1A1 | |
| SCHEMBL5327792 | 0.86 | HTR6 (0.52) | HTR6HSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL5333836 | 0.86 | HTR6 (0.52) | HTR6KMT2ADDR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |