Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.52 |
| ▸ | MPO | P05164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331983 | 0.94 | HTR6 (0.52) | HTR6MPOCYP3A4CYP2D6KMT2A | |
| SCHEMBL5330544 | 0.92 | HTR6 (0.43) | HTR6MPODRD2DRD4DRD3 | |
| SCHEMBL5335593 | 0.91 | MPO (0.46) | HTR6MPOCYP3A4CYP2D6DRD2 | |
| SCHEMBL5333028 | 0.90 | MPO (0.47) | HTR6MPOCYP3A4CYP2D6DRD2 | |
| SCHEMBL5332975 | 0.88 | HTR6 (0.50) | HTR6KMT2AALDH1A1 | |
| SCHEMBL5336272 | 0.87 | HSD17B10 (0.45) | HTR6KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5333836 | 0.86 | HTR6 (0.52) | HTR6MPOCYP3A4CYP2D6KMT2A | |
| SCHEMBL5335199 | 0.86 | HTR6 (0.46) | HTR6KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5333246 | 0.86 | POLB (0.45) | HTR6CYP3A4CYP2D6DRD2DRD4 | |
| SCHEMBL5329261 | 0.86 | HTR6 (0.49) | HTR6MPOCYP3A4CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |