Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333018 | 0.94 | DDR1 (0.43) | HSD17B10KMT2ADDR1HTR6ALDH1A1 | |
| SCHEMBL5335199 | 0.92 | HTR6 (0.46) | HSD17B10KMT2ADDR1HTR6ALDH1A1 | |
| SCHEMBL5331060 | 0.92 | ALDH1A1 (0.46) | HSD17B10KMT2ADDR1HTR6ALDH1A1 | |
| SCHEMBL5334580 | 0.90 | ALDH1A1 (0.44) | HSD17B10KMT2AHTR6ALDH1A1POLB | |
| SCHEMBL5330544 | 0.86 | HTR6 (0.43) | HSD17B10KMT2ADDR1HTR6ALDH1A1 | |
| SCHEMBL5332975 | 0.86 | HTR6 (0.50) | KMT2ADDR1HTR6ALDH1A1MEN1 | |
| SCHEMBL5335240 | 0.86 | ALDH1A1 (0.44) | HSD17B10KMT2ADDR1HTR6ALDH1A1 | |
| SCHEMBL5333822 | 0.86 | MAPT (0.45) | KMT2ADDR1HTR6MEN1MAPT | |
| SCHEMBL5337329 | 0.84 | DRD2 (0.44) | HSD17B10KMT2AHTR6ALDH1A1MEN1 | |
| SCHEMBL5328593 | 0.84 | ALDH1A1 (0.46) | KMT2ADDR1HTR6ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |