Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304682 | 0.87 | ALOX5 (0.43) | POLBSMN1; SMN2ALOX5LMNAABCB1 | |
| SCHEMBL1305107 | 0.86 | L3MBTL1 (0.41) | POLBSMN1; SMN2ALOX5HTTMAPT | |
| SCHEMBL1305429 | 0.86 | HDAC1 (0.46) | POLBSMN1; SMN2ALOX5GAAHTT | |
| SCHEMBL1304251 | 0.86 | LDHA (0.41) | POLBSMN1; SMN2ALOX5GAAMAPT | |
| SCHEMBL1304547 | 0.85 | MAPK1 (0.47) | POLBSMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL1305197 | 0.85 | POLB (0.39) | POLBSMN1; SMN2ALOX5GAAHTT | |
| SCHEMBL1304618 | 0.84 | ITGB3 (0.41) | POLBSMN1; SMN2ALOX5GAAHTT | |
| SCHEMBL1304974 | 0.81 | MAOB (0.38) | POLBSMN1; SMN2ALOX5PRSS1TMPRSS15 | |
| SCHEMBL1306105 | 0.81 | CYP1A2 (0.39) | POLBSMN1; SMN2ALOX5GAAHTT | |
| SCHEMBL1304563 | 0.81 | MAOA (0.39) | POLBSMN1; SMN2LMNAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044309-A2 | DEVICE AND METHOD FOR INHIBITING AGE COMPLEX FORMATION | VASIX CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-6337350-B1 | CROSSLINKING INHIBITION OF PROTEINS | CITY OF HOPE | 2002-01-08 | — | — | US | disclosed |