Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PPIA | P62937 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamethoxazole SCHEMBL3656 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL6896861 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL1368068 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL28501919 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL28142856 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL5870744 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL28565481 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL29625775 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL22467841 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL4539943 | 0.79 | ALDH1A1 (0.94) | ALDH1A1MAPTADRA1ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| EP-1675844-A1 | PHENYL CARBOXAMIDE AND SULFONAMIDE DERIVATIVES FOR USE AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE | Sterix Limited (GB) | 2006-07-05 | — | — | EP | disclosed |
| US-20050227987-A1 | 11beta-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2005-10-13 | — | — | US | disclosed |
| WO-2005042513-A1 | PHENYL CARBOXAMIDE AND SULFONAMIDE DERIVATIVES FOR USE AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE | STERIX LIMITED (GB) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227987-A1 | 11beta-hydroxysteroid dehydrogenase inhibitors | HSD3B1, HSD3B2, HSD17B3 | ALDH1A1 378/4885MAPT 4512/4885ADRA1A 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.