Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578078 | 0.93 | ALDH1A1 (0.72) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL27255797 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL7995097 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL6575565 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL27359831 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL4449137 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL9859129 | 0.86 | ALDH1A1 (0.71) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL108377 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL32670285 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRMAPK1CYP3A4LMNA | |
| SCHEMBL30823218 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRMAPK1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312266-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312266-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7250457-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-07-31 | — | — | US | disclosed |
| US-7250457-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-07-31 | — | — | US | disclosed |
| US-6927247-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1521803-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | The College of William and Mary (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2005-03-03 | — | — | US | disclosed |
| US-20040220310-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY | 2004-11-04 | — | — | US | disclosed |
| US-6762231-B2 | MERCAPTAN-CONTAINING ALIPHATIC DIESTER UTILIZED FOR HALOGEN-CONTAINING POLYMERS, ESPECIALLY POLY(VINYL CHLORIDE); | THE COLLEGE OF WILLIAM AND MARY | 2004-07-13 | — | — | US | disclosed |
| US-6747081-B2 | FOR DISCOLORATION INHIBITON OF HALOPOLYMERS SUCH AS POLYVINYL CHLORIDE POLY(VINYLIDENE CHLORIDE), POLY(VINYL BROMIDE), POLY(VINYLIDENE BROMIDE), CHLORINATED POLY(VINYL CHLORIDE), CHLORINATED POLYETHYLENE, CHLORINATED RUBBER | THE COLLEGE OF WILLIAM AND MARY | 2004-06-08 | — | — | US | disclosed |
| WO-2003106550-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2003-12-24 | — | — | WO | disclosed |
| US-6667357-B2 | Organic thiol is an aromatic compound having at least one sulfhydryl group attached indirectly or directly to a benzene ring | THE COLLEGE OF WILLIAM AND MARY | 2003-12-23 | — | — | US | disclosed |
| US-20030220429-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-11-27 | — | — | US | disclosed |
| US-20030055141-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-03-20 | — | — | US | disclosed |
| US-20020128363-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM & MARY (US) | 2002-09-12 | — | — | US | disclosed |
| US-20020115769-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM & MARY (US) | 2002-08-22 | — | — | US | disclosed |
| WO-2002048250-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | TST, LANCL1, TTPA | ALDH1A1 203/4885TSHR 2013/4885MAPK1 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.