Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007079 | 0.77 | NAAA (0.42) | SMN1; SMN2NPC1RAB9ALMNANAAA | |
| SCHEMBL533892 | 0.76 | TSHR (0.36) | LMNANAAAALDH1A1TSHR | |
| SCHEMBL10596280 | 0.72 | NR5A1 (0.38) | NR5A1KMT2ACYP2C9CYP2C19MEN1 | |
| SCHEMBL31215183 | 0.70 | CYP2C9 (0.34) | LMNANR5A1ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL9403662 | 0.69 | PTPN11 (0.49) | LMNAOPRK1ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL31215181 | 0.68 | CHRNA7 (0.33) | NR5A1ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8906187 | 0.68 | SLC6A3 (0.36) | KMT2AMEN1 | |
| SCHEMBL29001824 | 0.67 | NR5A1 (0.33) | NR5A1KMT2ACYP2C9CYP2C19MEN1 | |
| SCHEMBL10883785 | 0.66 | MEN1 (0.37) | SMN1; SMN2ALDH1A1KMT2ACYP2C9MEN1 | |
| SCHEMBL11158758 | 0.65 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670121-B2 | Diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2017-06-06 | — | — | US | claimed |
| US-20160060198-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2016-03-03 | — | — | US | claimed |
| US-9169187-B2 | Method of making peptides using diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2015-10-27 | — | — | US | claimed |
| US-20140213761-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC (JP) | 2014-07-31 | — | — | US | claimed |
| EP-2415745-A1 | DIPHENYLMETHANE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | claimed |
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-09-30 | — | — | US | claimed |
| WO-2025122535-A2 | LIQUID PHASE PEPTIDE SYNTHESIS METHODS | AMGEN INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| US-20250188118-A1 | LIQUID PHASE PEPTIDE SYNTHESIS METHODS | AMGEN INC. (US) | 2025-06-12 | — | — | US | disclosed |
| EP-3412689-B1 | HYDROGENATED BLOCK-COPOLYMER HAVING ACID ANHYDRIDE GROUP AND USE THEREOF | ZEON CORP (JP) | 2020-10-14 | — | — | EP | disclosed |
| US-20190203035-A1 | BLOCK-COPOLYMER HYDRIDE HAVING ACID ANHYDRIDE GROUP AND USE THEREOF | ZEON CORPORATION (JP) | 2019-07-04 | — | — | US | disclosed |
| EP-3412689-A1 | BLOCK-COPOLYMER HYDRIDE HAVING ACID ANHYDRIDE GROUP AND USE THEREOF | Zeon Corporation (JP) | 2018-12-12 | — | — | EP | disclosed |
| US-20180086029-A1 | RESIN COMPOSITION AND USE OF SAME | ZEON CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |
| EP-3281981-A1 | RESIN COMPOSITION AND USE OF SAME | Zeon Corporation (JP) | 2018-02-14 | — | — | EP | disclosed |
| US-9670121-B2 | Diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20160060198-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2016-03-03 | — | — | US | disclosed |
| US-9169187-B2 | Method of making peptides using diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20140213761-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC (JP) | 2014-07-31 | — | — | US | disclosed |
| US-8722934-B2 | Diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2014-05-13 | — | — | US | disclosed |
| EP-2415745-A1 | DIPHENYLMETHANE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, DNPEP, QPCTL | SMN1; SMN2 2836/4885NPC1 2869/4885RAB9A 4762/4885 |
| US-20250188118-A1 | LIQUID PHASE PEPTIDE SYNTHESIS METHODS | VIP, RNGTT, SSU72 | SMN1; SMN2 2212/4885NPC1 2397/4885RAB9A 4009/4885 |
| US-20140213761-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, VIP, CCKBR | SMN1; SMN2 2691/4885NPC1 2111/4885RAB9A 4622/4885 |
| US-20160060198-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, VIP, CCKBR | SMN1; SMN2 2691/4885NPC1 2111/4885RAB9A 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.